Rudd Lab

dNTP metabolism Molecular pharmacology

Our research centres upon understanding the molecular underpinnings of why some patients respond to therapies – in particular standard-of-care chemotherapeutics – whilst others do not, and using this knowledge as the basis for refining treatment strategies.

News

January, 2024

Our paper on the identification and evaluation of small molecule inhibitors of the drug resistance factor SAMHD1 is now published

Check out the accompanying news stories from Karolinska Institutet and SciLifeLab!

November, 2023

We're very happy and grateful to receive continued project funding from the Swedish Cancer Society (Cancerfonden)

September, 2023

Congratulations to Femke on winning the poster prize at the 20th KI-Cancer Research Retreat!

August, 2023

We welcome (back) Huazhang - new Research Assistant - to the group!

July, 2023

New review article on the importance of conventional chemotherapuetic agents now published

June, 2023

Congratulations to Femke on winning the poster prize at the Purine & Pyrimidine Society meeting in LA!

December, 2022

We're very happy and grateful to receive project funding from the Swedish Childhood Cancer Fund (Barncancerfonden)

September, 2022

We welcome Chris - new PhD student - to the group!

May, 2022

Our new review article on targeting nucleotide metabolism in cancer is now published

April, 2022

We're very happy to receive funding from the Dr Åke Olsson Foundation for Hematological Research

March, 2022

Congratulations to Miriam who has been awarded a postdoctoral fellowship from Barncancerfonden (Swedish Childhood Cancer Fund)

February, 2022

We're very happy our proposal for a Chemical Biology & Genome Engineering Platform Pilot Project has been selected for funding

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We are recruiting a PhD student! Get in touch if you're interested and check out the application for more details

November, 2021

We welcome Femke - new postdoc - to the group!

October, 2021

We're very happy to receive KID-funding from Karolinska Institutet, which will allow us to recruit a PhD student to the team!

April, 2021

Our new method paper on probing small molecule interaction with the dNTPase SAMHD1 is now published

March, 2021

We are recruiting a postdoc! Get in touch if you're interested and check out the application for more details

January, 2021

Our paper on drug synergy scoring of cancer therapeutics is now published

November, 2020

We're very happy and grateful to receive project funding from the Swedish Cancer Society (Cancerfonden)

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Our new preprint on drug synergy scoring of cancer therapuetics is up on bioRxiv

See also tweet thread summarising the story from Sean

October, 2020

We welcome Miriam - new postdoc - to the group!

July, 2020

Our new preprint on SAMHD1 and oncogene-induced replication stress is up on bioRxiv

April, 2020

We are recruiting a postdoc! Get in touch if you're interested

January, 2020

Our paper targeting the chemoresistance factor SAMHD1 with existing anticancer drugs is now published

See press release from Karolinska Instituet and tweet thread summarising the story from Sean