Rudd Lab
dNTP metabolism • Molecular pharmacology
Our research centres upon understanding the molecular underpinnings of why some patients respond to therapies – in particular standard-of-care chemotherapeutics – whilst others do not, and using this knowledge as the basis for refining treatment strategies.
News
January, 2024
Our paper on the identification and evaluation of small molecule inhibitors of the drug resistance factor SAMHD1 is now published
Check out the accompanying news stories from Karolinska Institutet and SciLifeLab!
November, 2023
We're very happy and grateful to receive continued project funding from the Swedish Cancer Society (Cancerfonden)
September, 2023
Congratulations to Femke on winning the poster prize at the 20th KI-Cancer Research Retreat!
August, 2023
We welcome (back) Huazhang - new Research Assistant - to the group!
July, 2023
New review article on the importance of conventional chemotherapuetic agents now published
June, 2023
Congratulations to Femke on winning the poster prize at the Purine & Pyrimidine Society meeting in LA!
January, 2023
Our new preprint on the identification and evaluation of small molecule inhibitors of the drug resistance factor SAMHD1 is up on bioRxiv
December, 2022
We're very happy and grateful to receive project funding from the Swedish Childhood Cancer Fund (Barncancerfonden)
September, 2022
We welcome Chris - new PhD student - to the group!
May, 2022
Our new review article on targeting nucleotide metabolism in cancer is now published
April, 2022
We're very happy to receive funding from the Dr Åke Olsson Foundation for Hematological Research
March, 2022
Congratulations to Miriam who has been awarded a postdoctoral fellowship from Barncancerfonden (Swedish Childhood Cancer Fund)
February, 2022
We're very happy our proposal for a Chemical Biology & Genome Engineering Platform Pilot Project has been selected for funding
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We are recruiting a PhD student! Get in touch if you're interested and check out the application for more details
November, 2021
We welcome Femke - new postdoc - to the group!
October, 2021
We're very happy to receive KID-funding from Karolinska Institutet, which will allow us to recruit a PhD student to the team!
April, 2021
Our new method paper on probing small molecule interaction with the dNTPase SAMHD1 is now published
March, 2021
We are recruiting a postdoc! Get in touch if you're interested and check out the application for more details
January, 2021
Our paper on drug synergy scoring of cancer therapeutics is now published
November, 2020
We're very happy and grateful to receive project funding from the Swedish Cancer Society (Cancerfonden)
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Our new preprint on drug synergy scoring of cancer therapuetics is up on bioRxiv
See also tweet thread summarising the story from Sean
October, 2020
We welcome Miriam - new postdoc - to the group!
July, 2020
Our new preprint on SAMHD1 and oncogene-induced replication stress is up on bioRxiv
April, 2020
We are recruiting a postdoc! Get in touch if you're interested
January, 2020
Our paper targeting the chemoresistance factor SAMHD1 with existing anticancer drugs is now published
See press release from Karolinska Instituet and tweet thread summarising the story from Sean