dNTP metabolism • Genome stability
Cancer biology & therapeutics
The Rudd lab investigates metabolic pathways operating inside cancer cells and how these pathways support malignant disease. We are particularly focused upon the metabolic interplay between the DNA precursor pool and the DNA molecule, a relationship that is fundamental to cancer biology, underpinning key aspects of oncogenesis together with therapy resistance. We apply a multidisciplinary approach centred upon gaining a detailed mechanistic understanding of these pathways, allowing the identification of potential biomarkers and therapeutic targets that can be exploited to rationally improve the treatment of cancer.
We're very happy to receive funding from the Dr Åke Olsson Foundation for Hematological Research
We're very happy our proposal for a Chemical Biology & Genome Engineering Platform Pilot Project has been selected for funding